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All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
Draws on 130 interviews---with scientists, clinicians, and women who have either donated or frozen their oocytes or received those of another woman---to trace how the history of human oocytes' perceived value intersects with the biological and social life of women.
Drawing on theories and concepts across medical sociology and parenting culture studies, as well as literature from demography, anthropology, law, and bioethics, this book examines women's motivations and experiences of social egg freezing in the context of debates surrounding reproductive choice and delayed motherhood.
Presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies.
This tells the story of doctors, researchers, and hopeful couples who pushed the limits of science and triggered a technological revolution in human reproduction. In so doing, they landed at the center of a controversy whose reverberations continue to this day.
In the United States, some 10% of people who wish to have children struggle with infertility. NOVA explores barriers to fertility, from the social to the biological, and the state of assisted reproductive technologies. Follow the journeys of people navigating challenges from structural inequalities and racism to falling sperm counts, egg freezing, and IVF.
To examine the psychological impact of fertility treatment suspensions resulting from the COVID-19 pandemic and to clarify psychosocial predictors of better or worse mental health. 92 women from Canada and the United States (ages 20-45 years) whose fertility treatments had been cancelled were recruited via social media. Participants completed a battery of questionnaires assessing depressive symptoms, perceived mental health impact, and change in quality of life related to treatment suspensions. Potential predictors of psychological outcomes were also examined, including several personality traits, aspects of social support, illness cognitions, and coping strategies.
Infertility is a condition that affects nearly 30 percent of women aged 25–44 in the United States. Though past research has addressed the stigmatization of infertility, few have done so in the context of stigma management between fertile and infertile women. In order to assess evidence of felt and enacted stigma, we employed a thematic content analysis of felt and enacted stigma in an online infertility forum, Fertile Thoughts, to analyze 432 initial threads by women in various stages of the treatment-seeking process.
In an effort to place the recent Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report publications regarding conception options for mixed-status couples with human immunodeficiency virus (HIV) in perspective, the researchers review the historical evolution of conception options for mixed-status couples with HIV with particular focus on the potential need for fertility treatment and the feasibility of accessing such treatment.
Are you trying to get pregnant? You might wonder whether there's anything you can do to make it easier to conceive. Some things might be beyond your control or need medical help. These include medical issues that affect being able to conceive. But your lifestyle choices can affect fertility too. Here's what you need to know.
Female fertility is being able to get pregnant. Have you and your partner been trying to get pregnant by having sex without birth control for at least one year with no success? Not getting pregnant in that time might make you wonder how fertile you are. Anyone can be affected by fertility concerns or problems.
Trouble releasing eggs, called ovulating, or trouble with regular periods. Hormone-related conditions can affect the release of eggs from the ovaries. These conditions include polycystic ovary syndrome, high prolactin hormone levels and thyroid conditions. Other conditions that may change ovulation or periods are poorly controlled diabetes and some autoimmune diseases such as lupus.
Aging. Waiting to try to get pregnant can lower the chance of being able to conceive. As you move closer to your 40s, you lose eggs at a faster rate. And the eggs you have are less likely to become fertile.
Try not to work the night shift. Working the night shift all the time might affect your hormone levels. This can raise the risk of not being fertile. If you do work the night shift, try to get enough sleep when you're not working.
Stress isn't likely to keep you from getting pregnant. But stress isn't good for your health. Think about ways to lower stress. Try meditation, deep breathing, yoga or other activities to lower and manage stress when you try to conceive.
Limit or avoid alcohol when trying to conceive. Heavy drinking is linked with an higher risk of problems ovulating. To help when you're trying to get pregnant, stop drinking alcohol. Not drinking is the best choice when you conceive and during pregnancy.
Don't exercise too hard or too long. For people at a healthy weight, too much hard exercise can affect ovulating and lower levels of the hormone progesterone. If you want to become pregnant soon, think about limiting hard exercise, such as running or fast cycling, to less than five hours a week and less than 60 minutes a day.
Dr Eliran Mor MDAvoid toxins. There are many toxins in the environment. These include pesticides, dry-cleaning solvents and lead. They can harm fertility. Be aware of these toxins and discuss ways to limit exposure to them with a member of your healthcare team.
STUDY QUESTION Is there evidence of a plateau in the cumulative live birth rate (cLBR) after a certain number of consecutive transfers of untested embryos? SUMMARY ANSWER In our cohort of 11 463 women, the cLBR continues to increase with each additional transfer of an untested embryo, reaching 68.3% after six blastocyst ...
STUDY QUESTION Can a video clip detailing the patient journey decrease women’s anxiety on the day of their first oocyte retrieval? SUMMARY ANSWER The video clip does not affect women’s anxiety on the day of their first oocyte retrieval. WHAT IS KNOWN ALREADY IVF triggers anxious reactions in women and men, with peaks of ...
STUDY QUESTION Do serum estradiol (E2) levels on the day of frozen blastocyst transfer (FBT) affect pregnancy outcomes in hormonal replacement therapy (HRT) cycles using transdermal estrogens? SUMMARY ANSWER E2 levels ≥313 pg/ml on the day of FBT are associated with increased early miscarriage rates (EMRs), but do not ...
STUDY QUESTION Is semen quality associated with the lifespan of men? SUMMARY ANSWER Men with a total motile sperm count of >120 million could expect to live 2.7 years longer than men with total motile sperm count of >0–5 million. WHAT IS KNOWN ALREADY Male infertility and semen quality have been suggested to be ...
STUDY QUESTION Does the intravenous administration of Atosiban around the time of frozen blastocyst transfer to reduce uterine contractility increase the likelihood of live birth in individuals undergoing ART treatment? SUMMARY ANSWER In individuals with a history of one previous implantation failure, Atosiban did not ...
STUDY QUESTION Does the objective and quantitative assessment of uterine tissue stiffness via ultrasound shear wave elastography (SWE) predict the outcome after single euploid frozen embryo transfer (FET)? SUMMARY ANSWER Uterine SWE data might be predictive of clinical pregnancy in good prognosis patients undergoing single ...
STUDY QUESTION Could real-time monitoring of volatile organic compounds (VOCs) in the embryology laboratory provide meaningful early warning for potential harm from the environment? SUMMARY ANSWER Even in a laboratory environment with a total VOC concentration lower than the recommendation of the Cairo Consensus, the ...
STUDY QUESTION How does two-consecutive single embryo transfer (2xSET) affect reproductive outcomes of IVF and ICSI compared to double embryo transfer (DET)? SUMMARY ANSWER Two-consecutive SET may provide greater or comparable live birth rate (LBR); with lower multiple birth, preterm birth, and pregnancy loss or neonatal ...
STUDY QUESTION Can a large-scale genome-wide association study (GWAS) meta-analysis identify genomic risk loci and likely involved genes for female genital tract (FGT) polyps, provide insights into the biological mechanism underlying their development, and inform of potential overlap with other traits, including ...
STUDY QUESTION How does the burden of somatic disorders compare between women with surgically verified endometriosis diagnosed in adolescence or early adulthood, and matched women without a history of endometriosis? SUMMARY ANSWER Women with endometriosis diagnosed at a young age had a higher incidence of several somatic ...
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Fertility counseling for transgender and gender diverse (TGD) people is a crucial aspect of their healthcare journey, since puberty suppression (PS) induced by a gonadotropin-releasing hormone (GnRH) agonist, gender affirming hormone treatment (GAHT) using testosterone or estrogen and an anti-androgen, and gender affirming surgery (GAS) affect the reproductive function. Fertility counseling can help individuals to make informed decisions about their reproductive goals and options, including options for preserving fertility. By providing comprehensive fertility counseling, healthcare providers can support the reproductive autonomy and overall well-being of TGD people.
The World Professional Association for Transgender Health (WPATH), American Society for Reproductive Medicine (ASRM), European Society of Human Reproduction and Embryology (ESHRE) and American College of Obstetricians and Gynecologists (ACOG) guidelines all stress the importance of fertility counseling, but lack specific recommendations for healthcare providers (Anderson et al., Citation2020; Coleman et al., Citation2022; Ethics Committee of the American Society for Reproductive Medicine, Citation2021; Silva, Citation2022).
This editorial aims to provide the most up-to-date guidance based on the latest literature from scientific guidelines (Coleman et al., Citation2022; Ethics Committee of the American Society for Reproductive Medicine, Citation2021; Silva, Citation2022), a recent systematic review (Stolk et al., Citation2023), and acDelphi study of Kolbuck et al. involving 80 experts in reproductive and pediatric transgender health care who consented on what to inform TGD adolescents and young adults concerning fertility (Kolbuck et al., Citation2020).
We consider that fertility counseling is effected by the legal, ethical and cultural background in every country. Therefore this guide has no strict rules or fixed regulations. The recommendations are based on the latest evidence and are a proposal for a counseling framework. The first part focuses on communication, and the second part focuses on the impact of medical transition on fertility and fertility preservation options.
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